Overview
As an infectious disease specialist and epidemiologist, Dr. Jessica Justman has worked for over two decades to advance HIV prevention, care, and treatment and, more recently, to pioneer a precision approach to understanding the global HIV epidemic.
As a Professor of Medicine in Epidemiology, Dr. Justman's research interests focus on HIV epidemiology and HIV prevention studies. For example, she spearheaded the CDC-funded Population-based HIV Impact Assessment (PHIA) Project. Since 2014, the PHIA Project's nationally representative surveys have measured access to care and treatment and, by using novel HIV recency assays, estimated HIV incidence in 15 African and Caribbean countries. Results from the PHIA surveys have transformed global HIV programming by highlighting the need for more effective and targeted HIV testing approaches. Dr. Justman is also principal investigator of the TRACE initiative, a technical assistance program that helps ministries of health use HIV recency testing to strengthen the precision of HIV infection surveillance systems and guide HIV prevention programs.
Dr. Justman's HIV prevention research began over 20 years ago when she was the site leader for ICAP's Bronx Prevention Center Clinical Research Site. The Bronx site, along with the Harlem Prevention Center and the Eswatini Prevention Center, is part of the NIH-funded ICAP at Columbia Clinical Trials Unit, for which Dr. Justman serves as co-principal investigator. With the advent of the SARS-CoV-2 pandemic, Dr. Justman has applied lessons from HIV programs and research to a wide range of COVID-19 activities, including COVID-19 surveys, vaccine trials, early treatment of COVID for close contacts, and treatment trials of monoclonal therapeutics.
She serves as ICAP's senior technical director and oversees the development and strengthening of ICAP's clinical, laboratory, strategic information and survey activities across a range of global projects.
Areas of Expertise / Conditions Treated
- HIV (Human Immunodeficiency Virus Infection)
- HIV/AIDS
- Tuberculosis
Academic Appointments
- Professor of Medicine (in Epidemiology and ICAP) at CUMC
Hospital Affiliations
- NewYork-Presbyterian / Columbia University Irving Medical Center
- NewYork-Presbyterian Allen Hospital
Gender
- Female
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Phone Appointments
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AETNA
- Aetna Signature Administrators
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Quality Health Management
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VNSNY CHOICE
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Credentials & Experience
Education & Training
- University of Rochester School of Medicine
- BS, 1981 Yale College
- MD, 1985 University of Rochester
- Residency: Montefiore Medical Center
- Fellowship: Montefiore Medical Center
Board Certifications
- Infectious Disease
- Internal Medicine
Research
Dr. Jessica Justman is an infectious disease specialist and global health expert, and has worked to advance HIV prevention, care, and treatment in sub-Saharan Africa and the United States by conducting HIV-focused epidemiology surveys and HIV prevention clinical research and overseeing public health service programs. She is an Associate Professor of Medicine in Epidemiology and Senior Technical Director at ICAP, a global public health center at the Mailman School of Public Health at Columbia University. In this role, she oversees the development and strengthening of ICAP's clinical, laboratory, strategic information and survey activities across a range of global projects.
Beginning in 2014, she spearheaded the PEPFAR-funded Population-based HIV Impact Assessment (PHIA) Project’s nationally representative surveys which have measured access to care and treatment and, by using novel HIV recency assays, HIV incidence in 20 African and Caribbean countries. Results from the PHIA surveys have transformed global HIV programming by highlighting the need for more effective and targeted HIV testing approaches. Dr. Justman is also principal investigator of the TRACE initiative, a technical assistance program supported by the US Center for Disease Control and Prevention, that helps ministries of health use HIV recency testing to strengthen the precision of HIV infection surveillance systems and guide HIV prevention programs.
Dr. Justman's HIV prevention research began over 20 years ago when she was the founding site leader for the NIH-funded Bronx Prevention Center clinical research site. The Bronx site, along with the Harlem Prevention Center and the Eswatini Prevention Center, is part of the ICAP at Columbia Clinical Trials Unit, for which Dr. Justman serves as co-principal investigator. These research sites have helped to conduct a wide range of HIV prevention research, including a trial of a novel long-acting, injectable formulation of cabotegravir, an antiretroviral agent, that was recently approved as pre-exposure prophylaxis by the US Food and Drug Administration based on findings from this study. With the advent of the SARS-CoV-2 pandemic, Dr. Justman has applied lessons from HIV programs and research to a wide range of COVID-19 activities, including COVID-19 surveys, vaccine trials, and early treatment trials.
Research Interests
- Biostatistical Methods
- Community Health
- HIV/AIDS
- Infectious Diseases
- Maternal and Reproductive Health
Selected Publications
Nkambule R, Philip NM, Reid G, Mnisi Z, Nuwagaba-Biribonwoha H, Ao TT, Ginindza C, Duong YT, Patel H, Saito S, Solmo C, Brown K, Moore CS, Voetsch AC, Bicego G, Bock N, Mhlanga F, Dlamini T, Mabuza K, Zwane A, Sahabo R, Dobbs T, Parekh BS, El-Sadr W, Ryan C, Justman J. HIV incidence, viremia, and the national response in Eswatini: Two sequential population-based surveys. PLoS One. 2021 Dec 2;16(12):e0260892. doi: 10.1371/journal.pone.0260892. PMID: 34855890; PMCID: PMC8639055.
O'Donnell MR, Grinsztejn B, Cummings MJ, Justman JE, Lamb MR, Eckhardt CM, Philip NM, Cheung YK, Gupta V, João E, Pilotto JH, Diniz MP, Cardoso SW, Abrams D, Rajagopalan KN, Borden SE, Wolf A, Sidi LC, Vizzoni A, Veloso VG, Bitan ZC, Scotto DE, Meyer BJ, Jacobson SD, Kantor A, Mishra N, Chauhan LV, Stone EF, Dei Zotti F, La Carpia F, Hudson KE, Ferrara SA, Schwartz J, Stotler BA, Lin WW, Wontakal SN, Shaz B, Briese T, Hod EA, Spitalnik SL, Eisenberger A, Lipkin WI. A randomized double-blind controlled trial of convalescent plasma in adults with severe COVID-19. J Clin Invest. 2021 Jul 1;131(13):e150646. doi: 10.1172/JCI150646. PMID: 33974559; PMCID: PMC8245169.
Duong YT, Dobbs T, Mavengere Y, Manjengwa J, Rottinghaus E, Saito S, Bock N, Philip N, Justman J, Bicego G, Nkengasong JN, Parekh BS. Field Validation of Limiting-Antigen Avidity Enzyme Immunoassay to Estimate HIV-1 Incidence in Cross-Sectional Survey in Swaziland. AIDS Res Hum Retroviruses. 2019 Oct;35(10):896-905. doi: 10.1089/AID.2018.0284. Epub 2019 Aug 15. PMID: 31204867.
Justman JE, Nair GL, Hendrix CW, Piper JM, Marzinke MA, Dai JY, Pan Z, Galaska B, Levy L, Schwartz JL, Balar B, Kunjara Na Ayudhya RP, Mushamiri I, McGowan I, Dezzutti CS; MTN-014 Study Team. Pharmacokinetics and Pharmacodynamics of Tenofovir Reduced-Glycerin 1% Gel in the Rectal and Vaginal Compartments in Women: A Cross-Compartmental Study With Directly Observed Dosing. J Acquir Immune Defic Syndr. 2018 Jun 1;78(2):175-182. doi: 10.1097/QAI.0000000000001655. PMID: 29767639; PMCID: PMC5963717.
Justman J, Reed JB, Bicego G, Donnell D, Li K, Bock N, Koler A, Philip NM, Mlambo CK, Parekh BS, Duong YT, Ellenberger DL, El-Sadr WM, Nkambule R. Swaziland HIV Incidence Measurement Survey (SHIMS): a prospective national cohort study. Lancet HIV. 2017 Feb;4(2):e83-e92. doi: 10.1016/S2352-3018(16)30190-4. Epub 2016 Nov 16. PMID: 27863998; PMCID: PMC5291824.