Sunil Kumar Dubey, PhD

  • Associate Research Scientist in the Center for Infection and Immunity

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Overview

Dubey works closely with Mishra in investigating humoral immune responses against viral pathogens to understand their implications in chronic infections. He is working on phage display development with Mishra to more accurately gauge the presence of antibodies against microbial pathogens in humans, animals, and wildlife. Combined with Dubey's experience with peptide microarrays, these innovative technologies cover a spectrum of both viruses and bacteria, which will potentially enhance the current studies on zoonotic diseases and reverse zoonoses.

Academic Appointments

  • Associate Research Scientist in the Center for Infection and Immunity

Research

Dr. Dubey is part of the team developing "A peptide microarray for serodiagnosis of exposure to high-threat hemorrhagic fever viruses", which is currently patent pending.

Research Interests

  • Infectious Diseases
  • Phage Display
  • Serology

Selected Publications

Dubey SK, Shrinet J, Sunil S. Aedes aegypti microRNA, miR-2944b-5p interacts with 3'UTR of chikungunya virus and cellular target vps-13 to regulate viral replication. PLoS Negl Trop Dis. 2019;13(6):e0007429. DOI: 10.1371/journal.pntd.0007429.

Shrinet J, Srivastava P, Kumar A, Dubey SK, Sirisena PDNN, Srivastava P, Sunil S. Differential Proteome Analysis of Chikungunya Virus and Dengue Virus Coinfection in Aedes Mosquitoes. J Proteome Res. 2018;17(10):3348-3359. DOI: 10.1021/acs.jproteome.8b00211.

Kumar A, Srivastava P, Sirisena P, Dubey SK, Kumar R, Shrinet J, Sunil S. Mosquito Innate Immunity. Insects. 2018;9(3):95. DOI: 10.3390/insects9030095.

Dubey SK, Shrinet J, Jaspreet J, Ali S, Sunil S. Aedes aegypti microRNA miR-2b regulates ubiquitin-related modifier to control chikungunya virus replication. Sci Rep. 2017;7(1):17666. DOI: 10.1038/s41598-017-18043-0.

Jain J, Dubey SK, Shrinet J, Sunil S. Dengue Chikungunya co-infection: A live-in relationship??. Biochem Biophys Res Commun. 2017;492(4):608-616. DOI: 10.1016/j.bbrc.2017.02.008.

Mathur K, Anand A, Dubey SK, Sanan-Mishra N, Bhatnagar RK, Sunil S. Analysis of chiungunya virus proteins reveals that non-structural proteins nsP2 and nsP3 exhibit RNA interference (RNAi) suppressor activity. Sci Rep. 2016;6:38065. DOI: 10.1038/srep38065