Dorottya Nagy-Szakal, MD, PhD

Postdoctoral Research Scientist
Phone: 212.305.3371
Fax: 212.342.9044
Email: dn2400@columbia.edu

EDUCATION & TRAINING

MD, Semmelweis University, Budapest, Hungary, 2009
PhD, Semmelweis University, Budapest, Hungary, 2017
Post-doctoral studies, Baylor College of Medicine and Texas Children's Hospital, Department of Pediatrics, Section of Pediatric Gastroenterology, Hepatology and Nutrition, Houston, TX, 2010-2015

RESEARCH INTERESTS

Pathogen Discovery and Identification 
Bioinformatic and Phylogenetic Analysis 
Nature of Mammalian Gut Microbiome
Pediatric Gastroenterology, Hepatology and Nutrition 
Environmental Effects and Dietary Influences on Pediatric Disease Pathomechanism

PUBLICATIONS

• Kellermayer R, Nagy-Szakal D, Harris RA, Luna RA, Pitashny M, Schady D, Mir SAV, Lopez, ME, Gilger MA, Belmont J, Hollister EB, Versalovic J. Serial Fecal Microbiota Transplantation Alters Mucosal Gene Expression in Pediatric Ulcerative Colitis. American Journal of Gastroenterology, 2015; 110(4):604-6.
• Nagy-Szakal D, Mir SA, Harris RA, Dowd SE, Yamada T, Lacorazza HD, Tatevian N, Smith CW, de Zoeten EF, Klein J, Kellermayer R. Loss of n-6 fatty acid induced pediatric obesity protects against acute murine colitis. FASEB J, 2015 Aug;29(8):3151-9. 
• Harris RA, Nagy-Szakal D, Mir SA, Frank E, Szigeti R, Kaplan JL, Bronsky J, Opekun A, Ferry GD, Winter H, Kellermayer R. DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis. Epigenetics, 2014 June;9(8)1131-7. 
• Mir SAV, Nagy-Szakal D, Dowd SE, Szigeti RG, Smith CW, Kellermayer R. Prenatal Methyl-Donor Supplementation Induces an Acute Colitis Prone Microbiome in Young Adult Mice. Plos One, 2013;8(8):e73162.
• Nagy-Szakal D, Hollister EB, Luna RA, Versalovic J, Smith CW, Kellermayer R. Cellulose Supplementation Early in Life Ameliorates Colitis in Adult Mice. Plos One, 2013;8(2):e56685. 
• Harris RA, Nagy-Szakal D, Kellermayer R. Human metastable epiallele candidates link to common disorders. Epigenetics, 2013 Jan;8(2):157-63.
• Nagy-Szakal D, Mir SA, Ross MC, Tatevian N, Petrosino JF, Kellermayer R. Monotonous Diets Protect against Acute Colitis in Mice: Epidemiologic and Therapeutic Implications. JPGN, 2013;56(5):544-50. 
• Kellermayer R, Mir SA, Nagy-Szakal D, Cox SB, Dowd SE, Kaplan JL, Sun Y, Reddy S, Bronsky J, Winter HS. Microbiome Separation and C - reactive protein Elevation in Treatment Naïve Pediatric Granulomatous Crohn Disease. JPGN, 2012 Sep;55(3):243-50. 
• Harris RA*, Nagy-Szakal D*, Pedersen N, Opekun A, Bronsky J, Munkholm P, Jespersgaard C, Andersen PS, Melegh B, Ferry G, Jess T, Kellermayer R. Genome Wide Peripheral Blood Leukocyte DNA Methylation Microarrays Identify a Single Association with Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2012; 18(12):2334-41. (*These authors contributed equally of this work.) 
• Szakál DN, Gyorffy H, Arató A, Cseh A, Molnár K, Papp M, Dezsofi A, Veres G. Mucosal expression of claudins 2, 3 and 4 in proximal and distal part of duodenum in children with coeliac disease. Virchows Arch. 2010 Mar; 456(3):245-250.