Statistical Genetics
Director: Prakash Gorroochurn, PhD
The Statistical Genetics Track of the MS degree program (MS/SG) trains students in the skills critical to the design and analysis of genetic data from human studies, touching upon clinical aspects, laboratory issues, and modern statistical analyses. Students take courses in human and population genetics, biostatistics, epidemiology, statistical genetics, and computational modeling. The program also emphasizes training in research communication skills to facilitate effective collaborations with scientists in other disciplines necessary in the rapidly changing field of genetics.
The MS/SG Track is intended for individuals who plan careers, or are actively engaged, in genetic research. Applicants to the track must, therefore, demonstrate an interest in genetics as well as a facility for quantitative reasoning.
The MS/SG may serve as a stand-alone degree or can be earned by graduate students who plan to pursue a doctorate at Columbia University or elsewhere. The track consists of 36 academic credits in addition to required capstone experience. The program usually requires at least three semesters of full-time study, and the typical time to completion is two years. If preferred, candidates may pursue the MS/SG degree on a part-time basis, but must complete the program within five years of the start date.
This is a very exciting time to be involved with statistical genetics as recent, and certainly future, discoveries will clearly continue to have a profound effect in public health and medicine.
Prakash Gorroochurn, PhD, Associate Professor of Clinical Biostatistics
Competencies
The MS in Biostatistics Statistical Genetics Track is intended to provide students with the skills to design and analyze research using genetic data from human studies. Competencies of the Statistical Genetics Track are achieved through a curriculum of at least 36 credit hours of coursework and the capstone experience.
Students in the Statistical Genetics Track gain the following competencies in the areas of data analysis and computing, public health and collaborative research, teaching statistical genetics, and statistical genetics research.
Upon satisfactory completion of the MS in Biostatistics Statistical Genetics Track, graduates will be able to:
- Demonstrate the correct use of probability distributions and theory of statistical inference within biostatistics and public health.
- Apply appropriate statistical methodology to analyze and interpret data from the public health, biomedical, or bioinformatics arena.
- Implement advanced techniques using statistical software to prepare written and oral presentations for disseminating findings.
- Apply principles of statistical genomics and computational genomics.
- Apply principles of population genetics to understand the extent of genetic variation in natural populations.
Course Requirements
The MS in Statistical Genetics curriculum is designed to achieve the program’s competencies through courses totaling 36 credit hours and the capstone experience. The curriculum includes 30 credits of required coursework and 6 credits of electives.
The required courses will enable degree candidates to gain proficiency in genetic study design and analysis. In rare circumstances, one or two required courses may be waived for students with demonstrated expertise in that field of study; however, students must still complete a minimum of 30 credits in order to be awarded the MS/SG degree. If a student places out of one or more required courses, s/he may instead opt to take a more advanced course in the same area or another elective course in Biostatistics or other discipline with the approval of the student’s faculty advisor.
Students wishing to waive one or more courses must request approval in writing from their advisors and the Director of Academic Programs.
Sample Timeline
Below is a sample timeline for MS/SG candidates. Note that course schedules change from year to year, so that class days/times in future years will differ from the sample schedule below; you must check the current course schedule for each year on the course directory page.
Fall I
- P8104: Probability
- P8105: Data Science I
- P8130: Biostatistical Methods I
- P8149: Human Population Genetics
Spring I
- P8109: Statistical Inference
- P8131: Biostatistical Methods II
- P8139: Statistical Genetics Modeling
- Elective
Fall II
- P6400: Principles of Epidemiology I
- P8119: Advanced Statistical & Computational Methods
- Elective
- Elective
Spring II
- P8185: Capstone Consulting Seminar
- Completion of practicum requirements
Practicum Requirement
One term of practical experience is required of all students, providing educational opportunities that are different from and supplementary to the more academic aspects of the program. The practicum may be fulfilled during the school year or over the summer. Arrangements are made on an individual basis in consultation with faculty advisors who must approve both the proposed practicum project prior to its initiation, and the report submitted at the conclusion of the practicum experience. Students will be required to make a poster presentation at the department’s Annual Practicum Poster Symposium which is held in early May.
Capstone Experience
P8185: Capstone Consulting Seminar
A formal, culminating experience for the MS degree is required for graduation. The capstone consulting seminar is designed to enable students to demonstrate their ability to integrate their academic studies with the role of biostatistical consultant/collaborator, which will comprise the major portion of their future professional practice.
As part of the seminar, students are required to attend several sessions of the Biostatistics Consulting Service (BCS). The Consultation Service offers advice on data analysis and appropriate methods of data presentation for publications, and provides design recommendations for public health and clinical research, including preparation of grant proposals. Biostatistics faculty and research staff members conduct all consultation sessions with students observing, modeling, and participating in the consultations.
In the capstone seminar, students present their experience and the statistical issues that emerged in their consultations, developing statistical report writing and presentation skills essential to their professional practice in biomedical and public health research projects.
P8163: Statistical Methods in Genetic Epidemiology Journal Club
This monthly Journal Club exposes students to current papers in genetic analysis. Additionally, each student must present at least one paper at the Journal Club over the course of his/her time in the program.
Contact
More information on Admission Requirements.